Na: The chemical
symbol for sodium. From natrium, a synonym for sodium. Sodium
chloride (ordinary salt) is NaCl.
Nail: In medicine, there are two types of nails. One is just a
plain old metal nail used to hold 2 or more pieces of bone
together, for example, after a fracture. The other type of nail
is the horny plate on the end of the finger or toe. Each nail
anatomically has a body, lateral nail folds (on the sides), a
lunula (the little moon-shaped feature at the base), and a
proximal skin fold (at the base).
Nail infection, fungal: The most common fungus infection of the
nails is onychomycosis. Onychomycosis makes the nails look white
and opaque, thickened, and brittle. Older women (perhaps because
estrogen deficiency may increase the risk of infection). and men
and women with diabetes or disease of the small blood vessels
(peripheral vacscular disease) are at increased risk. Artificial
nails (acrylic or "wraps") increase the risk because when an
artificial nail is applied, the nail surface is usually abraded
with an emery board damaging it, emery boards can carry
infection, and. water can collect under the nail creating a
moist, warm environment for fungal growth. Alternative names
include tinea unguium and ringworm of the nails.
Nails, ringworm of the: See Nail infection, fungal.
Nail-patella syndrome: An hereditary condition with abnormally
formed (dysplastic) or absent nails and absent or underdeveloped
(hypoplastic) kneecaps (patellae). Other features include iliac
horns, abnormality of the elbows interfering with full range of
motion (pronation and supination) and kidney disease resembling
glomerulonephritis which.is often mild but can be progressive
and lead to renal failure. Nail-patella syndrome is inherited as
dominant gene. This means that the disease can be transmitted by
one affected parent. The nail-patella gene locus found linked
genetically to the ABO blood group in 1965 is now known to be in
chromosome region 9q34. Also called Turner-Kieser syndrome, and
Fong disease.
Named reporting: In public health, named reporting is the
reporting of infected persons by name to public health
departments. This is standard practice for the surveillance of
many infectious diseases such as syphilis, gonorrhea, and
tuberculosis that pose a public health threat. The opposite of
named reporting is anonymous testing in which the individual
remains nameless.
Nanism: Once known as dwarfism, this condition is now correctly
called short stature.
Nares: The nostrils. The word "nares" is straight out of Latin
(still another reason why you should have taken Latin in school
or, if you did, studied harder).
Nasal: Having to do with the nose. Nasal drops are intended for
the nose, not (for example) the eyes. The word "nasal" came from
the Latin "nasus" meaning the nose or snout.
Nasal decongestants: Drugs that shrink the swollen membranes in
the nose and make it easier to breath. Decongestants can be
taken orally or by nasal spray. Decongestant nasal spray should
not be used for more than five days without the doctor"s advice,
and if so, usually only when accompanied by a nasal steroid.
Decongestant nasal sprays often cause a rebound effect if taken
too long. A rebound effect is the worsening of symptoms when a
drug is discontinued. This is a result of a tissue dependence on
the medication.
Nasal septum: The dividing wall that runs down the middle of the
nose so that there are normally two sides to the nose, each
ending in a nostril.
Nasopharynx: The area of the upper throat behind the nose.
Naturopath: A person who practices naturopathy, a drugless
system of therapy based on the use of physical forces such as
heat, water, light, air and Messages.
Navel: The umbilicus. The word navel came from the Anglo-Saxon
nafe for the hub of a wheel.
Nausea: Nausea is the urge to vomit. It can be brought by many
causes including, systemic illnesses, such as influenza,
medications, pain, and inner ear disease.
Neck dissection: Surgery to remove lymph nodes and other tissues
in the neck.
Neck, wry: Medically called spasmodic torticollis, or
torticollis. The most common of the focal dystonias. In
torticollis, the muscles in the neck that control the position
of the head are affected, causing the head to twist and turn to
one side. In addition, the head may be pulled forward or
backward.
Necropsy: A postmortem examination.
Necrosis: Death of cells or tissues. Necrosis can be due for
example to ischemia (lack of blood flow).
Necrotic: Synonymous with dead. Necrotic tissue is dead tissue.
Neisseria: Group of bacteria that includes the cause of
gonorrhea.
Nematodes: Roundworms.
Neo-: Prefix meaning new.
Neonatal: Pertaining to the newborn period which, by convention,
is the first 4 weeks after birth.
Neonatal mortality rate: The number of children dying under 28
days of age divided by the number of live births that year. The
neonatal mortality rate in the United States, which was 8.4 per
1,000 live births in 1980, declined to 5.8 per 1,000 live births
in 1990.
Neonate: A newborn baby.
Neonatologist: A specialist in the care of the newborn.
Neonatology: The art and science of caring medically for the
newborn.
Neoplasia: Abnormal new growth of cells.
Neoplasm: Literally, a new growth. Neoplasm is another word for
a tumor.
Nephrectomy: Surgery to remove the kidney. Radical nephrectomy
removed the kidney, the adrenal gland, nearby lymph nodes, and
other surrounding tissue. Simple nephrectomy removes just the
affected kidney. Partial nephrectomy removes the tumor, but not
the entire kidney.
Nephritis: Inflammation of the kidney.
Nephro-: Having to do with the kidney. From the Greek nephros
meaning kidney.
Nephrologist: A medical specialist in nephrology (the study of
the kidney or "kidney-ology").
Nephrology: The art and science of the care of the kidney.
Nephron: A key unit, both anatomically and functionally, of the
kidney.
Nephrosclerosis: Hardening (sclerosis) of the kidney usually due
to disease of the blood vessels in it from atherosclerosis.
Nephrosis: Non-inflammatory, non-neoplastic disease of the
kidney.
Nephrolithiasis: Kidney stones.
Nephrotomogram: A series of special x-rays of the kidneys. The
x-rays are taken from different angles. They show the kidneys
clearly, without the shadows of the organs around them.
Nerve: A nerve is a bundle of fibers that uses electrical and
chemical signals to transmit sensory and motor information from
one body part to another. (see nervous system).
Nerve Growth Factor: A substance that occurs naturally in the
body and enhances the growth and survival of cholinergic nerves.
Nervous colon syndrome: A common gastrointestinal disorder
characterized by abdominal pain, bloating, mucous in stools, and
irregular bowel habits with alternating diarrhea and
constipation, symptoms that tend to be chronic and wax and wane
over the years. Although nervous colon syndrome can cause
chronic recurrent discomfort, it appears to be an abnormal
condition of gut contractions (motility) and does not lead to
any serious organ problems. Diagnosis usually involves excluding
other illnesses. Treatment is directed toward relief of symptoms
and includes high fiber diet, exercise, relaxation techniques,
avoidance of caffeine, milk products and sweeteners, and
medications. Alternative names include irritable bowel syndrome,
spastic colitis, and mucus colitis.
Nervous system: The nervous system is the body tissue that
records and distributes information in the body using electrical
and chemical transmission. It has two parts. The "central"
nervous system is comprised of the brain and spinal cord. The
"peripheral" nervous system is the nerve tissue that transmits
sensation and motor information back and forth from the body to
the central nervous system.
Nervous system, autonomic: Part of the nervous system once
thought functionally independent of the brain. The autonomic
nervous system regulates key functions including the activity of
the cardiac (heart) muscle, smooth muscles (e.g., of the gut),
and glands. The autonomic nervous system has two divisions: (1)
the sympathetic nervous system, which accelerates the heart
rate, constricts blood vessels, and raises blood pressure; and
(2) the parasympathetic nervous system, which slows the heart
rate, increases intestinal and gland activity, and relaxes
sphincter muscles.
Nervous system, parasympathetic: A part of the nervous system
that slows the heart rate, increases intestinal and gland
activity, and relaxes sphincter muscles. The parasympathetic
nervous system together with the sympathetic nervous system
(that accelerates the heart rate, constricts blood vessels, and
raises blood pressure) constitute the autonomic nervous system.
Nervous system, sympathetic: A part of the nervous system that
accelerates the heart rate, constricts blood vessels, and raises
blood pressure. The sympathetic nervous system together with the
parasympathetic nervous system (that slows the heart rate,
increases intestinal and gland activity, and relaxes sphincter
muscles) constitute the autonomic nervous system.
Neural: Having to do with nerve cells.
Neural tube defect (NTD): Abnormal development during embryonic
life of the neural tube, the structure which gives rise to the
central nervous system (the brain and spinal cord), resulting in
anencephaly (absence of the cranial vault and absence of most or
all of the cerebral hemispheres of the brain) and spina bifida/meningomyelocele
(open spina with exposure and protusion of the spinal cord). The
risk of NTDs can be decreased by the mother eating ample folic
acid during pregnancy.
Neuralgia: Pain along the course of a nerve. Facial neuralgia is
severe pain usually occurrring in bursts from the trigeminal
nerve, the chief sensory nerve of the face.
Neuritis: Inflammation of nerves.
Neuroblastoma: Childhood tumor of adrenal or related tissue in
the nervous system.
Neurofibromatosis (NF1): Hereditary disorder characterized by
cafe-au-lait (coffee-with-milk spots on the skin and a tendency
to tumors) also known as von Recklinghausen's disease.
Neurogenic: Starting with or having to do with the nerves or the
nervous system.
Neurologist: A doctor who specializes in the diagnosis and
treatment of disorders of the nervous system.
Neuroma: A tumor that arises in nerve cells.
Neuroma, optic: A benign tumor of the optic nerve.
Neurosurgeon: A doctor who specializes in surgery on the brain
and other parts of the nervous system.
Neurosyphilis: The neurologic complications in the last
("tertiary") phase of syphilis involving the central nervous
system.
Neurosyphilis, tabes: Also known as tabes dorsalis, the slowly
progressive degeneration of the spinal cord that occurs in the
late (tertiary) phase of syphilis a decade or more after
contracting the infection. Among the terrible features are
lancinating lightning-like pain, ataxia (wobbliness),
deterioration of the nerve to the eye (the optic nerve) leading
to blindness, urinary incontinence, loss of the sense of
position, and degeneration of the joints (Charcot’s joints).
Tabes is the Latin word for decay. The term tabes dorsalis was
devised in 1836 when the cause of the condition was thought to
be wastage of the dorsal (posterior) columns of the spinal cord,
well before it was recognized as part of late syphilis.
Neurotoxic: Poisonous to nerves or nerve tissue. (example: lead)
Neutropenia: Not enough neutrophils.
Neutrophil: A type of white blood cell.
Neutrophilia: Too many neutrophils.
Nevus: A pigmented spot on the skin, such as a mole. The plural
of nevus is nevi.
Newborn screening: Tests of newborns to detect those at
increased risk for disorders such as PKU (phenylketonuria) and
hypothyroidism.
NIH: The National Institutes of Health.
Nipple: The pigmented projection on the surface of the breast.
Ducts which conduct milk from milk glands to the surface of the
breast exit through the nipple. The surrounding flat area of
pigmentation is the areola.
Nipple, supernumerary: An extra nipple.
Nitrogenous base: A molecule that contains nitrogen and has the
chemical properties of a base. The nitrogenous bases in DNA are
adenine (A), guanine (G), thymine (T), and cytosine ©. The
nitrogenous bases in RNA are the same with one exception:
adenine (A), guanine (G), uracil (U), and cytosine ©
Nitrosoureas: A group of anticancer drugs that can cross the
blood-brain barrier. Carmustine (BCNU) and lomustine (CCNU) are
nitrosoureas.
NMR: Nuclear Magnetic Resonance. An imaging technique that does
not use radiation.
Nocturia: Excessive urinating at night.
Node: Literally a knot, a node is a collection of tissue. For
example a lymph node, is a collection of lymphoid tissue.
Node, AV: Atrioventricular node. Specialized heart tissue which
acts as an electrical relay station between the upper chambers
of the heart (atria) and the lower chambers of the heart
(ventricles). Electrical signals from the sinoatrial (SA) node
and the atria must pass through the AV node to reach the
ventricles.
Node, SA: Sinoatrial node. The pacemaker of the heart, located
in the right atrium (upper chamber of the heart). The electrical
signals initiated in the SA node are transmitted throuhg the
atria and the ventricles to stimulate heart muscle contractions
(heartbeats).
Nodular: Bumpy.
Nodule: A small node, a bump.
Nondisjunction: Failure of paired chromosomes to disjoin
(separate) during cell division so both chromosomes go to one
daughter cell and none to the other. Nondisjunction causes
errors in chromosome number such as trisomy 21 (Down syndrome)
and monsomy X (Turner syndrome).
Nonmelanoma skin cancer: Skin cancer that does not involve
melanocytes. Basal cell cancer and squamous cell cancer are
nonmelanoma skin cancers.
Nonseminoma: A classification of testicular cancers that arise
in specialized sex cells called germ cells. Nonseminomas include
embryonal carcinoma, teratoma, choriocarcinoma, and yolk sac
tumor.
Nonsense mutation: A change in a DNA that prematurely stops the
eading of messenger RNA. A nonsense mutation creates a stop
codon (a triplet of bases that signals stop).
Nonsmall cell lung cancer: A general classification for squamous
cell carcinoma, adenocarcinoma, and large cell carcinoma.
Normal range: Normal results can fall outside the normal range.
By convention, the normal range is set to cover ninety-five
percent (95%) of values from a normal population. Five percent
(5%) of normal results therefore fall outside the normal range.
North Asian tick-borne rickettsiosis: One of the tick-borne
rickettsial diseases of the eastern hemisphere, similar to Rocky
Mountain spotted fever, but less severe, with fever, a small
ulcer (eschar) at the site of the tick bite, swollen glands
nearby (satellite lymphadenopathy), and a red raised (maculopapular)
rash.
Northern blot: A technique in molecular biology, used mainly to
separate and identify pieces of RNA. Called a Northern blot
because it is similar to a Southern blot (which is named after
its inventor, the British biologist M.E. Southern).
Nosebleed: Its medical name is epistaxis.
Nosebleed, causes of: The nose is a part of the body that is
very rich in blood vessels (vascular) and is situated in a
vulnerable position on the face. As a result, any trauma to the
face can cause bleeding which may be profuse. Nosebleeds can
occur spontaneously when the nasal membranes dry out, crust, and
crack, as is common in dry climates, or during the winter months
when the air is dry and warm from household heaters. People are
more susceptible if they are taking medications which prevent
normal blood clotting (coumadin, warfarin, aspirin, or any
anti-inflammatory medication). Other predisposing factors
include infection, trauma, allergic and non-allergic rhinitis,
hypertension., alcohol abuse and inherited bleeding problems.
Nosebleed, treatment of: To stop a nosebleed, you should: 1.
Pinch all the soft parts of the nose together between your thumb
and index finger. 2. Press firmly toward the face - compressing
the pinched parts of the nose against the bones of the face. 3.
Hold the nose for at least 5 minutes (timed by the clock).
Repeat as necessary until the nose has stopped bleeding. 4. Sit
quietly, keeping the head higher than the level of the heart;
that is, sit up or lie with the head elevated. Do not lay flat
or put your head between your legs. 5. Apply ice (crushed in a
plastic bag or washcloth) to nose and cheeks.
Nose job: Plastic surgery on the nose known medically as a
rhinoplasty.
Nose, runny: Rhinorrhea is the medical term for this common
problem. From the Greek words "rhinos" meaning "of the nose" and
"rhoia" meaning "a flowing."
Nosocomial: Hospital-acquired. A nosocomial infection is one
contracted in the hospital.
NSAIDS: Abbreviation for nonsteroidal anti-inflammatory drugs.
This is a large group of medications used to treat conditions
associated with inflammation.
NTD: Neural tube defect.
Nucleic acid: DNA or RNA.
Nucleosome: Structure responsible in part for the compactness of
a chromosome. Each nucleosome consists of a sequence of DNA
wrapped around a core of histone (a type of protein).
Nucleotide: A subunit of DNA or RNA. A nucleotide consists of a
nitrogenous base (A, G, T, or C in DNA; A, G, U, or C in RNA), a
phosphate molecule, and a sugar molecule (deoxyribose in DNA and
ribose in RNA). Thousands of nucleotides are linked to form a
DNA or RNA molecule.
Nucleus: In cell biology, the structure that houses the
chromosomes. In neuroanatomy, a group of nerve cells.
Nullipara: A woman who has not given birth to a viable child.
Null mutation: Change in a gene that leads to nothing, for
example to no enzyme or to a nonfunctioning enzyme.
Nurse: A person skilled in nursing. Also, to feed at the breast
(suckle) as an infant.
Nursing: Profession (better known than defined) concerned with
the provision of services essential to the maintenance and
restoration of health by attending the needs of sick persons.
Also, feeding a infant at the breast.
Nutrition: The science of taking in and utilizing foods.
Nutritionist: A specialist in nutrition.
Nystagmus: Rapid rhythmic repetitious involuntary (unwilled) eye
movements. Nystagmus can be horizontal, vertical or rotary.
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